Abstract: With the continuous advancement in artificial lacrimal duct improvements and tissue transplantation, significant progress has been made in the clinical treatment of lacrimal duct obstruction. However, complications such as postoperative scar obstruction or inflammatory reactions have not been completely resolved. Previous studies mainly focused on optimizing artificial lacrimal duct improvements, but it is currently difficult to achieve better clinical outcomes through surgical modifications. With the development of molecular biology and tissue engineering techniques, new scaffold materials are continuously being developed, providing a broad prospect for the treatment of lacrimal duct obstruction. Silicone-based materials, widely used in clinical tear duct intubation, still need improvement in terms of tissue compatibility compared to polypropylene and polymer materials. The development of new biodegradable materials indicates a new research direction for tear duct intubation materials. In addition, the combination of autologous and allogeneic materials provides a new developmental direction for tear duct bypass reconstruction surgery without the need for internal support.(Int Rev Ophthalmol, 2023, 47: 367-372)

Key words: lacrimal duct obstruction, support materials